Paul Sieber, MD

Paul Sieber, M.D. is the Medical Director for Clinical Trials at Keystone Urology. He went to Purdue University and obtained his undergraduate degree in Biology before receiving his medical degree from Indiana University. He did his residency in general surgery and urology at the M.S. Hershey Medical Center, Penn State University. He has been involved with clinical trials for 20 years having worked on more than 200 studies. The bulk of these have focused on prostate cancer. Dr. Sieber is very enthusiastic about clinical trials and research as he looks at what can benefit his patients in the future. Many of today’s state-of-the-art treatments for prostate cancer have been investigated right here in Lancaster including Xgeva, Zytiga, Xtandi, Erleada, and Firmagon. Numerous diagnostic tests including OncotypeDX, Prolaris, Decipher, and 4K score have also been studied here. Furthermore, Keystone Urology has been a long-term participant in CAPSURE, an observational database with more than 150 publications. Dr. Sieber has authored numerous peer-reviewed articles and presented many posters at meetings including the AUA, ASCO, ASCO GU, SUO, and SIU.

Dr. Sieber met his wife of over 35 years while at Hershey Medical Center and has three children. Dr. Sieber enjoys spending time with his wife, gardening, exercising / cycling, and traveling.