Dr. Matthew G. Yantis, M.D., earned his B.S. in Biology from Rhodes College in Memphis, TN, graduating Cum Laude and as a member of Phi Beta Kappa. He completed his medical degree at the University of Tennessee, where he developed a passion for head and neck anatomy and ENT care. Dr. Yantis then completed his Otolaryngology internship and residency at the University of Texas Medical Branch in Galveston, excelling in research and earning awards for his contributions.
Dr. Matthew G. Yantis, M.D., earned his B.S. in Biology from Rhodes College in Memphis, TN, graduating Cum Laude and as a member of Phi Beta Kappa. He completed his medical degree at the University of Tennessee, where he developed a passion for head and neck anatomy and ENT care. Dr. Yantis then completed his Otolaryngology internship and residency at the University of Texas Medical Branch in Galveston, excelling in research and earning awards for his contributions.
Dr. Matthew G. Yantis, M.D., grew up in Chattanooga, TN, and received his B.S. degree in Biology at Rhodes College in Memphis, TN, where he graduated Cum Laude and was inducted into the Phi Beta Kappa honor society. He then received his medical degree at the University of Tennessee, where he developed a passion for the anatomy of the head and neck as well as caring for diseases of the ear, nose, and throat.
Along with his wife Elyssa, who is a board-certified pediatrician, he moved to Galveston, Texas where he completed his internship and residency in Otolaryngology at the University of Texas Medical Branch. Throughout his residency, he excelled—presenting his research at national ENT meetings and winning the Residency Research Award. He was also nominated for the Best Overall Resident in the hospital and won the Outstanding Overall Resident in Otolaryngology award.
After completing residency Dr. Yantis was ready to escape the Texas heat and be closer to family. He found a welcoming home in Louisville where he was thrilled to join Advanced ENT & Allergy. For his medical practice, he enjoys all facets of Otolaryngology, including care of sinus and allergy issues, along with surgery of the sinuses, including non-invasive techniques such as in-office balloon sinuplasty. He has significant experience in the evaluation and treatment of thyroid and parathyroid disorders, including advanced training in thyroid and neck ultrasound. He also enjoys caring for children and the various pediatric ENT problems that arise including tonsil and adenoid disease, ear and allergy concerns, as well as infections of the head and neck. He is also trained in sleep apnea surgery including the new innovative Inspire device (hypoglossal nerve stimulator), an alternative to CPAP.
Dr. Yantis and his wife enjoy time with their children Crisman, Olivia, and Lucy. In his free time, he enjoys playing tennis, spending time with his dogs and kids, playing and listening to music, and participating in outdoor activities and water sports such as boating and jet skiing.

My daughter was referred to him for a couple ear infections. Went to the very first appointment and he didn’t want to wait to put tubes in, his only fix for the ear infections were getting tubes no other option was giving. Got tubes in July. Had two ear infections in August one of them which landed us in the er and she is now having yet again another ear infection that needs more than ear drops to fix it. All he does is blame her being sick for the ear infections but she’s getting sick after starting the medication for the ear infections. When seen in the room he rushes the whole appointment. He doesn’t let you ask any questions until he brings you to check out and he continues to rush you. While we were there for the last appointment I had multiple questions that kept leading to the same answer, “it’s because she’s sick” when she wasn’t sick when she was diagnosed with it. But not only was that the response he was also huffing and puffing and smacking his teeth with every question.
Easy to talk with. Helps explain everything needing to happen and provides options to choose from.
Very nice.
He is very thorough very nice
Dr. Yantis listened to my concerns and seemed very thorough and helpful.
Highly recommend Dr. Yantis! He was very thorough and listened intently to my history of symptoms! I had nasal endoscopy on the spot and was put at ease prior to ever leaving the office! Thank you for such great care!
Dr Yantis is awesome he listens but straight to the point and very workable I love that he includes you in on treatment my daughter loves going to see him she thinks he's just her doctor
Takes the time to listen and answer any questions you might have.
Terrific doctor. Explained everything very clearly.
Dr Yantis performed a procedure on gland under my tongue that was blocked by a 1.5mm stone. I had a CT scan the day before. The procedure was very uncomfortable/painful for me, but Dr Yantis talked me through it. He was calm and assured and got most of the stone out. We thought he was kind, helpful, knowledgeable, personable, and reassuring.