Dr. Matthew Appenzeller, M.D. is a specialist in medical and surgical treatment of the vitreous, retina, diabetic eye diseases and cataracts. Dr. Appenzeller is Board Certified in Ophthalmology and is a member of the American Academy of Ophthalmology, the American Society of Retina Specialists and the Nebraska Association of Eye Physicians and Surgeons (NAEPS). He served as president for NAEPS in 2018.
Dr. Matthew Appenzeller, M.D. is a specialist in medical and surgical treatment of the vitreous, retina, diabetic eye diseases and cataracts. Dr. Appenzeller is Board Certified in Ophthalmology and is a member of the American Academy of Ophthalmology, the American Society of Retina Specialists and the Nebraska Association of Eye Physicians and Surgeons (NAEPS). He served as president for NAEPS in 2018.
Dr. Matthew Appenzeller, M.D. is a specialist in medical and surgical treatment of the vitreous, retina, diabetic eye diseases and cataracts.
A native of South Carolina, Dr. Appenzeller received his bachelor’s degree in biology and dramatic art at the University of North Carolina at Chapel Hill. After graduation, he was accepted into Teach for America, and he taught eight- and ninth-grade science in rural Louisiana for two years. It was during his time in the student clinic that he realized an appreciation for medicine, and he decided to leave teaching and enter medical school.
Dr. Appenzeller returned to South Carolina to attend the Medical University of South Carolina. He completed a one-year internship in internal medicine and a three-year residency in ophthalmology at the University of Cincinnati. Dr. Appenzeller completed his formal medical training with a fellowship in Vitreo-retinal surgery and medicine at the Cincinnati Eye Institute.
After his fellowship program, Dr. Appenzeller moved to North Carolina to practice at Alamance Eye Center from 2010 to 2015. During that time, his wife began studies for a PhD in Early Childhood Development and Deaf Education. Upon approaching completion of her degree, the couple began searching for a city that would provide a professional home for both of them. Dr. Appenzeller and his family are very excited to move to Omaha.
Dr. Appenzeller is Board Certified in Ophthalmology and is a member of the American Academy of Ophthalmology, the American Society of Retina Specialists and the Nebraska Association of Eye Physicians and Surgeons (NAEPS). He served as president for NAEPS in 2018.

He takes into consideration the full needs of the patient, the body and treats accordingly . Gives painless eye injections!
Excellent doctor, he saved my sight when I had a retinal detachment and I want to continue as his patient for as long as he practices in Omaha.
I appreciate I have appointments on days where the office isn’t incredibly busy. Doctor gets me in and out and honors my time.
My recent appointment with Dr. Appenzeller was really good. The information I was looking for and options for treatment were provided in a clear and comfortable manner. Highly recommended.
Dr. Appenzeller always explains what he is doing. I appreciate knowing what he is doing, what the outcome should be and if there is anymore that can be done.
He is a great Dr he did a great job on my eyes. So happy I went to him.
Very knowledgeable
Great doctor
Continues to provide a high level of knowledge and compassion
He's very knowledgable.