Dr. Matheen A. Khuddus, M.D. is a graduate of the University of Florida College of Medicine and completed his Residency in Internal Medicine as well as his Fellowship training in Cardiology and Interventional Cardiology at the University of Florida. He joined The Cardiac & Vascular Institute in 2008. He is certified by the American Board of Internal Medicine in Cardiovascular Medicine, Interventional Cardiology, and Internal Medicine. He is also board certified in Nuclear Cardiology and is an American Society of Hypertension Certified Specialist in Clinical Hypertension.
Dr. Matheen A. Khuddus, M.D. is a graduate of the University of Florida College of Medicine and completed his Residency in Internal Medicine as well as his Fellowship training in Cardiology and Interventional Cardiology at the University of Florida. He joined The Cardiac & Vascular Institute in 2008. He is certified by the American Board of Internal Medicine in Cardiovascular Medicine, Interventional Cardiology, and Internal Medicine. He is also board certified in Nuclear Cardiology and is an American Society of Hypertension Certified Specialist in Clinical Hypertension.
The reviews listed below were collected independently of The Cardiac and Vascular Institute through rater8. Each review represents an authentic and verified patient experience.
Very helpful and informative
(3 weeks ago)
Mar-2026
He does a wonderful job thank you
(3 weeks ago)
Feb-2026
Very informative and willing to explain reasoning for any changes in medications and or any new plans for care going forward.
(3 weeks ago)
Feb-2026
Focused, attentive and direct. No fluff but clearly explained all the next steps
(1 month ago)
Feb-2026
A joy to interact with!
(1 month ago)
Feb-2026
Listened to me, answered all my questions.
(1 month ago)
Feb-2026
Great cardiologist. Someone i trust my life to. Can't say that about some doctors I've been to.
(1 month ago)
Feb-2026
Dr Khuddus is THE BEST! He’s professional, attentive, personable takes the time necessary to answer questions and provide insight and explanations about his recommended treatment & medication choices. Hopefully he never leaves TCAVI!
(1 month ago)
Feb-2026
Too early to tell.
Seemed great
(1 month ago)
Feb-2026
Have seen Dr Khuddus since September 3008 when he put my stent in. He’s closely monitoring my carotid arteries now as well. He is very thorough and kept monitoring my LDl and suggested I use Repatha since I have SLE and sent the dietician in my hospital room to check on my diet. He concluded that my Lupus was the problem and needed to use Repatha since since a statin and a good diet were not sufficient to get my LDL where he wanted it. My care with Dr Khuddus iOS is always excellent
(1 month ago)
Jan-2026
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TCAVI: Gainesville East Office
4645 NW 8th Avenue Gainesville, FL 32605
TCAVI: Gainesville West Office
1151 NW 64th Terrace Gainesville, FL 32605
TCAVI: Lake City Office
3239 NW York Drive Lake City, FL 32055
Dr. Matheen A. Khuddus, M.D. is a native of South Florida and is a graduate of the University of Florida College of Medicine, Junior Honors Medical Program. He completed his Residency in Internal Medicine as well as his Fellowship training in Cardiology and Interventional Cardiology at the University of Florida. He joined The Cardiac & Vascular Institute in 2008 and currently serves as the Medical Director and the Director of Cardiovascular Research.
Dr. Khuddus maintains several professional associations including designations as a Fellow of the American College of Cardiology and the Society of Cardiovascular Interventions and Angiography. He is certified by the American Board of Internal Medicine in Cardiovascular Medicine, Interventional Cardiology, and Internal Medicine. He is also board certified in Nuclear Cardiology and is an American Society of Hypertension Certified Specialist in Clinical Hypertension.
His primary areas interests include the treatment of complex coronary artery disease, radial artery access for cardiac catheterization and the endovascular treatment of peripheral arterial disease including carotid disease, critical limb ischemia and emerging interventional techniques for the treatment of hypertension. He is the primary investigator on several clinical trials evaluating novel device and drug therapies for the treatment of coronary artery and peripheral vascular disease. Dr. Khuddus has co-authored book chapters and Continuing Medical Education activities as well as contributing to magazines and peer reviewed journals covering various topics in cardiovascular medicine.
Dr. Khuddus remains active in the community frequently participating in community educational events and supporting the American Heart Association. He is currently a board member of the Alachua County Medical Society. In his spare time, he enjoys fishing, traveling and spending time with his wife and three children.
See other doctors in The Cardiac and Vascular Institute
Very helpful and informative
He does a wonderful job thank you
Very informative and willing to explain reasoning for any changes in medications and or any new plans for care going forward.
Focused, attentive and direct. No fluff but clearly explained all the next steps
A joy to interact with!
Listened to me, answered all my questions.
Great cardiologist. Someone i trust my life to. Can't say that about some doctors I've been to.
Dr Khuddus is THE BEST! He’s professional, attentive, personable takes the time necessary to answer questions and provide insight and explanations about his recommended treatment & medication choices. Hopefully he never leaves TCAVI!
Too early to tell. Seemed great
Have seen Dr Khuddus since September 3008 when he put my stent in. He’s closely monitoring my carotid arteries now as well. He is very thorough and kept monitoring my LDl and suggested I use Repatha since I have SLE and sent the dietician in my hospital room to check on my diet. He concluded that my Lupus was the problem and needed to use Repatha since since a statin and a good diet were not sufficient to get my LDL where he wanted it. My care with Dr Khuddus iOS is always excellent