Dr. Matheen A. Khuddus, M.D. is a graduate of the University of Florida College of Medicine and completed his Residency in Internal Medicine as well as his Fellowship training in Cardiology and Interventional Cardiology at the University of Florida. He joined The Cardiac & Vascular Institute in 2008. He is certified by the American Board of Internal Medicine in Cardiovascular Medicine, Interventional Cardiology, and Internal Medicine. He is also board certified in Nuclear Cardiology and is an American Society of Hypertension Certified Specialist in Clinical Hypertension.
Dr. Matheen A. Khuddus, M.D. is a graduate of the University of Florida College of Medicine and completed his Residency in Internal Medicine as well as his Fellowship training in Cardiology and Interventional Cardiology at the University of Florida. He joined The Cardiac & Vascular Institute in 2008. He is certified by the American Board of Internal Medicine in Cardiovascular Medicine, Interventional Cardiology, and Internal Medicine. He is also board certified in Nuclear Cardiology and is an American Society of Hypertension Certified Specialist in Clinical Hypertension.
The reviews listed below were collected independently of The Cardiac and Vascular Institute through rater8. Each review represents an authentic and verified patient experience.
Covered all questions and took the time to explain all aspects of diagnosis
(1 week ago)
Apr-2026
A friendly Doctor who cares. The best I ever had.
(1 week ago)
Apr-2026
Dr Khuddus never lets me down! He’s always a 10+
(1 week ago)
Apr-2026
He took time to explain the test results and to listen/answer my questions. Very professional and thorough.
(2 weeks ago)
Mar-2026
Always good
(3 weeks ago)
Mar-2026
Very helpful and informative
(1 month ago)
Mar-2026
He does a wonderful job thank you
(1 month ago)
Feb-2026
Very informative and willing to explain reasoning for any changes in medications and or any new plans for care going forward.
(1 month ago)
Feb-2026
Focused, attentive and direct. No fluff but clearly explained all the next steps
(1 month ago)
Feb-2026
A joy to interact with!
(1 month ago)
Feb-2026
Read More
TCAVI: Gainesville East Office
4645 NW 8th Avenue Gainesville, FL 32605
TCAVI: Gainesville West Office
1151 NW 64th Terrace Gainesville, FL 32605
TCAVI: Lake City Office
3239 NW York Drive Lake City, FL 32055
Dr. Matheen A. Khuddus, M.D. is a native of South Florida and is a graduate of the University of Florida College of Medicine, Junior Honors Medical Program. He completed his Residency in Internal Medicine as well as his Fellowship training in Cardiology and Interventional Cardiology at the University of Florida. He joined The Cardiac & Vascular Institute in 2008 and currently serves as the Medical Director and the Director of Cardiovascular Research.
Dr. Khuddus maintains several professional associations including designations as a Fellow of the American College of Cardiology and the Society of Cardiovascular Interventions and Angiography. He is certified by the American Board of Internal Medicine in Cardiovascular Medicine, Interventional Cardiology, and Internal Medicine. He is also board certified in Nuclear Cardiology and is an American Society of Hypertension Certified Specialist in Clinical Hypertension.
His primary areas interests include the treatment of complex coronary artery disease, radial artery access for cardiac catheterization and the endovascular treatment of peripheral arterial disease including carotid disease, critical limb ischemia and emerging interventional techniques for the treatment of hypertension. He is the primary investigator on several clinical trials evaluating novel device and drug therapies for the treatment of coronary artery and peripheral vascular disease. Dr. Khuddus has co-authored book chapters and Continuing Medical Education activities as well as contributing to magazines and peer reviewed journals covering various topics in cardiovascular medicine.
Dr. Khuddus remains active in the community frequently participating in community educational events and supporting the American Heart Association. He is currently a board member of the Alachua County Medical Society. In his spare time, he enjoys fishing, traveling and spending time with his wife and three children.
See other doctors in The Cardiac and Vascular Institute
Covered all questions and took the time to explain all aspects of diagnosis
A friendly Doctor who cares. The best I ever had.
Dr Khuddus never lets me down! He’s always a 10+
He took time to explain the test results and to listen/answer my questions. Very professional and thorough.
Always good
Very helpful and informative
He does a wonderful job thank you
Very informative and willing to explain reasoning for any changes in medications and or any new plans for care going forward.
Focused, attentive and direct. No fluff but clearly explained all the next steps
A joy to interact with!