Dr. John DeStafeno, M.D. is a board-certified ophthalmologist specializing in all aspects of refractive cataract surgery and laser surgery as well as the treatment of complex corneal diseases. He completed his 2-year fellowship at Duke University which focused on clinical research and the medical and surgical management of anterior segment disease.
Dr. John DeStafeno, M.D. is a board-certified ophthalmologist specializing in all aspects of refractive cataract surgery and laser surgery as well as the treatment of complex corneal diseases. He completed his 2-year fellowship at Duke University which focused on clinical research and the medical and surgical management of anterior segment disease.
Dr. John DeStafeno, M.D. is a board-certified ophthalmologist specializing in all aspects of refractive cataract surgery and laser surgery as well as the treatment of complex corneal diseases. He completed his 2-year fellowship at Duke University which focused on clinical research and the medical and surgical management of anterior segment disease.
Dr. DeStafeno has brought several innovative medical and surgical treatments to our area and is an experienced all-laser LASIK surgeon. In addition, Dr. DeStafeno was the first surgeon in Chester County to perform DSAEK corneal transplantation.
Recognized both locally and nationally for his excellence in eye care, Dr. DeStafeno has received numerous Top Doctor and Surgeon Awards. For the past several years, he has been selected by peers to instruct the LASIK Surgery Course at the annual American Academy of Ophthalmology meeting. Dr. DeStafeno also enjoys educating the future of eye care, instructing ophthalmology residents at Wills Eye Hospital at Thomas Jefferson.
EDUCATION
Graduated Summa Cum Laude, Siena/Albany Medical College Program in Science and Humanities, Albany, NY
Doctor of Medicine degree from Albany Medical College
Residency in Ophthalmology at Long Island Jewish Hospital, Albert Einstein College of Medicine, serving as chief resident senior year
Two-year Clinical/Research Fellowship in Cornea, Refractive, and External Disease at the Duke University Eye Center, Duke College of Medicine
POSITION AND DISTINCTIONS
Attending Surgeon at the Chester County Hospital
Certified Intralase LASIK surgeon
Certified Wavelight LASIK surgeon
Clinical Instructor for residents at Wills Eye Hospital/Thomas Jefferson University Hospital
Founding member Vanguard Ophthalmology Society
Instructor, LASIK Surgery Course, American Academy of Ophthalmology
AWARDS AND HONORS
American Academy of Ophthalmology Achievement Award
Top 300 Refractive Cataract Surgeons by Ocular Surgery News
Top Doctor in Main Line Today magazine
Top Doctor in Philadelphia magazine
Top 250 Premium IOL Surgeons in Premier Surgeon magazine
Alpha Omega Alpha Medical Honor Society
PERSONAL SNIPPET
Originally from New York, Dr. DeStafeno has grown to love Chester County and the Philadelphia region. He enjoys supporting local community arts, festivals, and sporting events with his wife and three children. He also loves playing tennis and traveling with his friends and family.

Everyone was wonderful. Thank you!
Dr. DeStafeno radiates confidence in his stellar surgical skills while being reassuring and kind. He and his staff made this surgery a pleasant experience and I’m enjoying my very clear vision!
I’m very pleased with the results of my cataract surgery. The process was seamless and procedures were timely, painless and successful. Dr. Destafeno was courteous and receptive to questions. The post surgery flowers and candy and mugs were a thoughtful gesture and appreciated. I would recommend Dr. Destafeno to others.
He explained everything very well and clearly discussed options
Kind, knowledgeable and quick!
professional and thourogh.
Great explaining procedure and results.
Process is very comprehensive. Doctor DeStefano was very helpful and explained my options well.
I am scheduled for cataract surgery for both eyes. Dr. DeStafeno explained in detail the procedure after doing his eye exam. His excellent staff performed all the cataract tests. It was a smooth process.
I appreciate his calm nature and how he made sure I was well informed.