Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
The reviews listed below were collected independently of EmergeOrtho through rater8. Each review represents an authentic and verified patient experience.
Very kind & knowledgeable
(5 days ago)
Jun-2026
Doctor Karegeannes is always very thoughtful. Listens carefully and makes things happen with as little pain as possible.
(1 week ago)
Jun-2026
Dr. Karegeannes was very helpful.
(2 weeks ago)
May-2026
Best doctor ever. I trust my life to him. I am grateful for his education, training, experience, compassion, empathy. Hugs to you, Doctor K.
(2 weeks ago)
May-2026
Very caring and understanding.
(3 weeks ago)
May-2026
He has restored my faith in MDs. Dr K is caring and honest re what works great, what doesn’t work well and what won’t help at all. He’s just a good, smart guy!…and a superior surgeon!
(3 weeks ago)
May-2026
Open to discussing info with client
(1 month ago)
Apr-2026
Very kind and very experienced. Im happy to have him fof my upcoming hip surgery.
(1 month ago)
Apr-2026
Dr Karegeannes is excellent he tells it straight about arthritis, he is kind soft spoken and very efficient. It’s a busy office. They offer easy checking when you get in, they send paper work the day before to update info. Very easy.!
(1 month ago)
Apr-2026
Dr. Karegeannes is excellent and definitely wants to make the patient feel better. Fantastic doctor.
(1 month ago)
Apr-2026
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Blue Ridge Region: Asheville - McDowell - Orthopedics
129 McDowell Street Asheville, NC 28801
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy. He then returned to Duke for his Orthopedic Surgery Training followed by a Hip and Knee Replacement Fellowship at The Hospital for Special Surgery in New York City.
He specializes in hip and knee replacement surgery, as well as revision surgery for failed replacements. He performs more than 450 joint replacement surgeries per year. He was named one of the “Top Doctors” for Hip and Knee Arthroplasty, Money magazine, Special Report, “The Best Health Care in America”, in fall 2003. He reviews articles the Journal of Arthroplasty and cases for the North Carolina Medical Board. He is currently the chief of the Orthopedic service line at Mission HCA hospital in Asheville.
He is active in local and national joint replacement organizations to help ensure that patients in our region can access the latest treatment options. He does not accept consulting fees or other payments from joint implant manufacturers to ensure his recommendations for treatment are unbiased and place his patients’ interests first.
Outside the office, he enjoys spending time with his wife, two adult children and one large hound dog. He serves on the local Boy Scout council executive board, enjoys hiking, gardening and burrowing into old books on food and drink culture.
Very kind & knowledgeable
Doctor Karegeannes is always very thoughtful. Listens carefully and makes things happen with as little pain as possible.
Dr. Karegeannes was very helpful.
Best doctor ever. I trust my life to him. I am grateful for his education, training, experience, compassion, empathy. Hugs to you, Doctor K.
Very caring and understanding.
He has restored my faith in MDs. Dr K is caring and honest re what works great, what doesn’t work well and what won’t help at all. He’s just a good, smart guy!…and a superior surgeon!
Open to discussing info with client
Very kind and very experienced. Im happy to have him fof my upcoming hip surgery.
Dr Karegeannes is excellent he tells it straight about arthritis, he is kind soft spoken and very efficient. It’s a busy office. They offer easy checking when you get in, they send paper work the day before to update info. Very easy.!
Dr. Karegeannes is excellent and definitely wants to make the patient feel better. Fantastic doctor.