Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
The reviews listed below were collected independently of EmergeOrtho through rater8. Each review represents an authentic and verified patient experience.
The physician was personable, connected and provided sound medical advice.
(6 days ago)
Jul-2026
Very friendly and took the time to explain my surgery details and how the knee looked from the X-rays. Very happy with my procedure and the outcome.
(1 week ago)
Jul-2026
Dr. K is the best. Sixteen years ago he did a knee revision and did a tune-up on my other knee. Both knees have lots of mileage. He listens and provides clear advice.
(2 weeks ago)
Jul-2026
Always very nice
(2 weeks ago)
Jul-2026
He seems like able and very knowledgeable. I have not been pleased with the office though.
(3 weeks ago)
Jun-2026
Always does a 👍👍
(3 weeks ago)
Jun-2026
My gosh to guy!
(3 weeks ago)
Jun-2026
The best of the best
(3 weeks ago)
Jun-2026
Very kind & knowledgeable
(1 month ago)
Jun-2026
Doctor Karegeannes is always very thoughtful. Listens carefully and makes things happen with as little pain as possible.
(1 month ago)
Jun-2026
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Blue Ridge Region: Asheville - McDowell - Orthopedics
129 McDowell Street Asheville, NC 28801
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy. He then returned to Duke for his Orthopedic Surgery Training followed by a Hip and Knee Replacement Fellowship at The Hospital for Special Surgery in New York City.
He specializes in hip and knee replacement surgery, as well as revision surgery for failed replacements. He performs more than 450 joint replacement surgeries per year. He was named one of the “Top Doctors” for Hip and Knee Arthroplasty, Money magazine, Special Report, “The Best Health Care in America”, in fall 2003. He reviews articles the Journal of Arthroplasty and cases for the North Carolina Medical Board. He is currently the chief of the Orthopedic service line at Mission HCA hospital in Asheville.
He is active in local and national joint replacement organizations to help ensure that patients in our region can access the latest treatment options. He does not accept consulting fees or other payments from joint implant manufacturers to ensure his recommendations for treatment are unbiased and place his patients’ interests first.
Outside the office, he enjoys spending time with his wife, two adult children and one large hound dog. He serves on the local Boy Scout council executive board, enjoys hiking, gardening and burrowing into old books on food and drink culture.
The physician was personable, connected and provided sound medical advice.
Very friendly and took the time to explain my surgery details and how the knee looked from the X-rays. Very happy with my procedure and the outcome.
Dr. K is the best. Sixteen years ago he did a knee revision and did a tune-up on my other knee. Both knees have lots of mileage. He listens and provides clear advice.
Always very nice
He seems like able and very knowledgeable. I have not been pleased with the office though.
Always does a 👍👍
My gosh to guy!
The best of the best
Very kind & knowledgeable
Doctor Karegeannes is always very thoughtful. Listens carefully and makes things happen with as little pain as possible.