Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
The reviews listed below were collected independently of EmergeOrtho through rater8. Each review represents an authentic and verified patient experience.
Very confident in him and his doctrine with my bilateral knee problems. He always gives me his recommendations and explains why.
(1 week ago)
Dec-2025
Very caring… excellent “bedside manner”…has good solutions to problems…
(2 weeks ago)
Nov-2025
Appreciate his talent and skills.
(2 weeks ago)
Nov-2025
It’s always a pleasure dealing with Dr. Karegeannes.
(3 weeks ago)
Nov-2025
Very ice visit w him very knowledgeable and helpful.. he is going forward w more appointments to try to answer my area s of concern.. did not give up on me .. I appreciate him greatly
(3 weeks ago)
Nov-2025
Excellent in every way -explanations, options, patience as well as surgical treatment and post treatment.
I am so glad that I found him and will continue to go to him as long as he and I are around
(3 weeks ago)
Nov-2025
Doc was relaxed and present as we discussed options. He provided a wealth of info in a manner that was easy to digest. I appreciate the time he sat with me as much as the way he approached my knee repair problems.
(1 month ago)
Oct-2025
He is the very best . My third joint replacement proved by him. Excellent service & very caring.
(1 month ago)
Oct-2025
Dr. Karegeannes Is an excellent physician and orthopedic surgeon.
(1 month ago)
Oct-2025
He outstanding It understands exactly what you're asking his answers are specific to where you can understand them.
(1 month ago)
Oct-2025
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Blue Ridge Region: Asheville - McDowell - Orthopedics
129 McDowell Street Asheville, NC 28801
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy. He then returned to Duke for his Orthopedic Surgery Training followed by a Hip and Knee Replacement Fellowship at The Hospital for Special Surgery in New York City.
He specializes in hip and knee replacement surgery, as well as revision surgery for failed replacements. He performs more than 450 joint replacement surgeries per year. He was named one of the “Top Doctors” for Hip and Knee Arthroplasty, Money magazine, Special Report, “The Best Health Care in America”, in fall 2003. He reviews articles the Journal of Arthroplasty and cases for the North Carolina Medical Board. He is currently the chief of the Orthopedic service line at Mission HCA hospital in Asheville.
He is active in local and national joint replacement organizations to help ensure that patients in our region can access the latest treatment options. He does not accept consulting fees or other payments from joint implant manufacturers to ensure his recommendations for treatment are unbiased and place his patients’ interests first.
Outside the office, he enjoys spending time with his wife, two adult children and one large hound dog. He serves on the local Boy Scout council executive board, enjoys hiking, gardening and burrowing into old books on food and drink culture.
Very confident in him and his doctrine with my bilateral knee problems. He always gives me his recommendations and explains why.
Very caring… excellent “bedside manner”…has good solutions to problems…
Appreciate his talent and skills.
It’s always a pleasure dealing with Dr. Karegeannes.
Very ice visit w him very knowledgeable and helpful.. he is going forward w more appointments to try to answer my area s of concern.. did not give up on me .. I appreciate him greatly
Excellent in every way -explanations, options, patience as well as surgical treatment and post treatment. I am so glad that I found him and will continue to go to him as long as he and I are around
Doc was relaxed and present as we discussed options. He provided a wealth of info in a manner that was easy to digest. I appreciate the time he sat with me as much as the way he approached my knee repair problems.
He is the very best . My third joint replacement proved by him. Excellent service & very caring.
Dr. Karegeannes Is an excellent physician and orthopedic surgeon.
He outstanding It understands exactly what you're asking his answers are specific to where you can understand them.