Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
The reviews listed below were collected independently of EmergeOrtho through rater8. Each review represents an authentic and verified patient experience.
Dr. Karegeannes is an outstanding physician. He is able to diagnose your symptoms and make a recommendation for a cure. He is very knowledgeable, patient, understanding, and straightforward. He truly cares about his patients. I highly recommend Dr. Karegeannes.
(1 week ago)
Feb-2026
Very professional and informative!
Great appt. with Dr. Karegeannes exceptional ...as well as his physicians assistance!
(1 week ago)
Feb-2026
One of the best doctors i've ever met and take so much time with you. At my age that means a lot to me. So very thankful for your doctors and staff at Emergeortho-Blue Rudge. Sue G
(1 week ago)
Feb-2026
Dr KAREGEANNES did a great job on my total knee replacement. Top Notch.
(2 weeks ago)
Feb-2026
The best
(3 weeks ago)
Feb-2026
Dr. James C. Karegeannes was easy to talk to and took the time to explain my broken wrist clearly. He kept me well informed and answered my questions, which made the experience reassuring.
(3 weeks ago)
Feb-2026
He is great surgeon and sots an talks to you
(3 weeks ago)
Feb-2026
Explained things in detail and spent time doing so.
(3 weeks ago)
Feb-2026
Kind. Professional.
(1 month ago)
Jan-2026
Excellent personal style and excellent skills!
(1 month ago)
Jan-2026
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Blue Ridge Region: Asheville - McDowell - Orthopedics
129 McDowell Street Asheville, NC 28801
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy. He then returned to Duke for his Orthopedic Surgery Training followed by a Hip and Knee Replacement Fellowship at The Hospital for Special Surgery in New York City.
He specializes in hip and knee replacement surgery, as well as revision surgery for failed replacements. He performs more than 450 joint replacement surgeries per year. He was named one of the “Top Doctors” for Hip and Knee Arthroplasty, Money magazine, Special Report, “The Best Health Care in America”, in fall 2003. He reviews articles the Journal of Arthroplasty and cases for the North Carolina Medical Board. He is currently the chief of the Orthopedic service line at Mission HCA hospital in Asheville.
He is active in local and national joint replacement organizations to help ensure that patients in our region can access the latest treatment options. He does not accept consulting fees or other payments from joint implant manufacturers to ensure his recommendations for treatment are unbiased and place his patients’ interests first.
Outside the office, he enjoys spending time with his wife, two adult children and one large hound dog. He serves on the local Boy Scout council executive board, enjoys hiking, gardening and burrowing into old books on food and drink culture.
Dr. Karegeannes is an outstanding physician. He is able to diagnose your symptoms and make a recommendation for a cure. He is very knowledgeable, patient, understanding, and straightforward. He truly cares about his patients. I highly recommend Dr. Karegeannes.
Very professional and informative! Great appt. with Dr. Karegeannes exceptional ...as well as his physicians assistance!
One of the best doctors i've ever met and take so much time with you. At my age that means a lot to me. So very thankful for your doctors and staff at Emergeortho-Blue Rudge. Sue G
Dr KAREGEANNES did a great job on my total knee replacement. Top Notch.
The best
Dr. James C. Karegeannes was easy to talk to and took the time to explain my broken wrist clearly. He kept me well informed and answered my questions, which made the experience reassuring.
He is great surgeon and sots an talks to you
Explained things in detail and spent time doing so.
Kind. Professional.
Excellent personal style and excellent skills!