Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy.
The reviews listed below were collected independently of EmergeOrtho through rater8. Each review represents an authentic and verified patient experience.
Dr. K was very attentive, professional and informative. He answered pinpointed my issues, answered my concerns and offered a resolution. OURSTANDING. I wish I'd known Dr. K prior to my surgeries in 2024 and 2025
(4 days ago)
Mar-2026
Dr Karegeannes was friendly, thorough and informative about my hip issue. He offered several options for future treatment. A great experience.
(5 days ago)
Mar-2026
So far I would recomend him.
(1 week ago)
Mar-2026
Dr. Karegeannes it’s very good at what he does. I’m so glad I found him.
(1 week ago)
Mar-2026
Excellent orthopedist, surgeon and long- term orthopedic care.
(2 weeks ago)
Mar-2026
He was my rehab coach today providing encouraging and specific information about my recovery. I appreciate him sharing his knowledge and expertise.
(2 weeks ago)
Mar-2026
Good listener, fast to diagnose problems.
(2 weeks ago)
Mar-2026
Kind, compassionate, and offers great communication. An excellent experience.
(3 weeks ago)
Feb-2026
Dr. Karegeannes is an outstanding physician. He is able to diagnose your symptoms and make a recommendation for a cure. He is very knowledgeable, patient, understanding, and straightforward. He truly cares about his patients. I highly recommend Dr. Karegeannes.
(1 month ago)
Feb-2026
Very professional and informative!
Great appt. with Dr. Karegeannes exceptional ...as well as his physicians assistance!
(1 month ago)
Feb-2026
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Blue Ridge Region: Asheville - McDowell - Orthopedics
129 McDowell Street Asheville, NC 28801
Dr. James C. Karegeannes [Care-ah-gene-us] graduated magna cum laude from the University of South Carolina Honors Program. In addition to being named a National Merit Scholar, he was also a member of Phi Beta Kappa. He completed medical school at Duke University. Dr. Karegeannes completed his internship at the San Diego Naval Hospital. This was followed by three years as a Submarine and Diving Medical Officer in the Navy. He then returned to Duke for his Orthopedic Surgery Training followed by a Hip and Knee Replacement Fellowship at The Hospital for Special Surgery in New York City.
He specializes in hip and knee replacement surgery, as well as revision surgery for failed replacements. He performs more than 450 joint replacement surgeries per year. He was named one of the “Top Doctors” for Hip and Knee Arthroplasty, Money magazine, Special Report, “The Best Health Care in America”, in fall 2003. He reviews articles the Journal of Arthroplasty and cases for the North Carolina Medical Board. He is currently the chief of the Orthopedic service line at Mission HCA hospital in Asheville.
He is active in local and national joint replacement organizations to help ensure that patients in our region can access the latest treatment options. He does not accept consulting fees or other payments from joint implant manufacturers to ensure his recommendations for treatment are unbiased and place his patients’ interests first.
Outside the office, he enjoys spending time with his wife, two adult children and one large hound dog. He serves on the local Boy Scout council executive board, enjoys hiking, gardening and burrowing into old books on food and drink culture.
Dr. K was very attentive, professional and informative. He answered pinpointed my issues, answered my concerns and offered a resolution. OURSTANDING. I wish I'd known Dr. K prior to my surgeries in 2024 and 2025
Dr Karegeannes was friendly, thorough and informative about my hip issue. He offered several options for future treatment. A great experience.
So far I would recomend him.
Dr. Karegeannes it’s very good at what he does. I’m so glad I found him.
Excellent orthopedist, surgeon and long- term orthopedic care.
He was my rehab coach today providing encouraging and specific information about my recovery. I appreciate him sharing his knowledge and expertise.
Good listener, fast to diagnose problems.
Kind, compassionate, and offers great communication. An excellent experience.
Dr. Karegeannes is an outstanding physician. He is able to diagnose your symptoms and make a recommendation for a cure. He is very knowledgeable, patient, understanding, and straightforward. He truly cares about his patients. I highly recommend Dr. Karegeannes.
Very professional and informative! Great appt. with Dr. Karegeannes exceptional ...as well as his physicians assistance!