Dr. James Killeffer, M.D. is Board Certified by the American Board of Neurological Surgery and is a Fellow of the American Association of Neurological Surgeons. He completed medical school at the University of Tennessee in Memphis, completed a general surgery internship at the University of Tennessee Graduate School of Medicine, and completed his neurosurgical residency at West Virginia University, where he joined their faculty as an Instructor in Neurosurgery.
Dr. James Killeffer, M.D. is Board Certified by the American Board of Neurological Surgery and is a Fellow of the American Association of Neurological Surgeons. He completed medical school at the University of Tennessee in Memphis, completed a general surgery internship at the University of Tennessee Graduate School of Medicine, and completed his neurosurgical residency at West Virginia University, where he joined their faculty as an Instructor in Neurosurgery.
The reviews listed below were collected independently of Neurosurgical Associates, P.C. through rater8. Each review represents an authentic and verified patient experience.
Was very helpful. Answers my question. Would recommend him to anyone who needs his care.
(5 days ago)
Mar-2026
One of the best doctors I have met
(5 days ago)
Mar-2026
Excellent in every respect
(2 weeks ago)
Mar-2026
Very pleasant and talked in terms easily understood. In a couple of short visits I totally trust Dr Killifer with repairing my neck issues.
(1 month ago)
Feb-2026
A caring caring doctor we need more of dr killefer in this world
(6 months ago)
Sep-2025
Very professional, compassionate, caring, and knowledgeable.
(7 months ago)
Aug-2025
Very efficient office
(7 months ago)
Jul-2025
Doesn’t talk “above my head”! Is friendly and respectful. Worked around other medical conditions and concerns. He is great and so is his staff. I highly recommend him
(8 months ago)
Jun-2025
Very personable. Extremely thoughtful in analyzing the problem. Seems very concerned with my particular problem. Very confident but also measured with caution to verify diagnosis. Top notch doctor.
(8 months ago)
Jun-2025
It is always a good visit. Very respectful. The staff are great.
(9 months ago)
Jun-2025
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UT Office
1932 Alcoa Hwy Bldg. C, Suite 360 Knoxville, TN 37920
Dr. James Killeffer, M.D. has practiced neurosurgery in Knoxville since 1997. He is Board Certified by the American Board of Neurological Surgery and is a Fellow of the American Association of Neurological Surgeons. He grew up in Knoxville and graduated from the University of Tennessee with Honors in 1987. He completed medical school at the University of Tennessee in Memphis, completed a general surgery internship at the University of Tennessee Graduate School of Medicine, and completed his neurosurgical residency at West Virginia University, where he joined their faculty as an Instructor in Neurosurgery. He returned to Knoxville to join his father in practice at University Neurosurgery, PC.
Dr. Killeffer became a full-time member of the faculty of the University of Tennessee Graduate School of Medicine in 2006. His duties there as Chief of the Division of Neurosurgery and Assistant Professor of Surgery include directing resident and medical student education and participating in neurosurgery-related research.
He has published articles on numerous topics including cervical spine anatomy, spinal imaging, intracranial subdural hematoma, brain tumors, spinal anomalies, intravenous nutrition, and the socio-economic aspects of neurosurgery. Currently, he is collaborating with members of the Engineering Department at the University of Tennessee and with engineers in the private sector in research involving cerebrospinal fluid flow dynamics and the kinematics of brain trauma. He also is working with engineers to develop implants to improve the treatment of cerebrospinal fluid circulation disorders.
Dr. Killeffer’s clinical practice includes treatment of a broad spectrum of adult neurosurgical problems including the brain, spine, and peripheral nerve surgery. Special interests include minimally invasive techniques in brain and spinal surgery, endoscopic pituitary surgery, trigeminal neuralgia, and hemifacial spasm, and surgical neuro-oncology, including brain and spinal stereotactic radiosurgery. He practices at an academic teaching hospital to give his patients access to the state-of-the-art comprehensive care of neurosurgical problems.
See other doctors in Neurosurgical Associates, P.C.
Was very helpful. Answers my question. Would recommend him to anyone who needs his care.
One of the best doctors I have met
Excellent in every respect
Very pleasant and talked in terms easily understood. In a couple of short visits I totally trust Dr Killifer with repairing my neck issues.
A caring caring doctor we need more of dr killefer in this world
Very professional, compassionate, caring, and knowledgeable.
Very efficient office
Doesn’t talk “above my head”! Is friendly and respectful. Worked around other medical conditions and concerns. He is great and so is his staff. I highly recommend him
Very personable. Extremely thoughtful in analyzing the problem. Seems very concerned with my particular problem. Very confident but also measured with caution to verify diagnosis. Top notch doctor.
It is always a good visit. Very respectful. The staff are great.