Dr. D. Isaac Gaines, M.D. received his undergraduate degree in biology from Birmingham-Southern College in Alabama. He continued with his education and graduated from the University of Alabama-School of Medicine, where he also completed his internship and residency. He was chosen to be the chief resident and instructor before deciding to pursue a fellowship at the Medical University of South Carolina for gastroenterology and hepatology.
Dr. D. Isaac Gaines, M.D. received his undergraduate degree in biology from Birmingham-Southern College in Alabama. He continued with his education and graduated from the University of Alabama-School of Medicine, where he also completed his internship and residency. He was chosen to be the chief resident and instructor before deciding to pursue a fellowship at the Medical University of South Carolina for gastroenterology and hepatology.
The reviews listed below were collected independently of Gastroenterology Associates through rater8. Each review represents an authentic and verified patient experience.
Great
(5 days ago)
Aug-2026
He made me feel at ease . Very personable.
(2 weeks ago)
Jul-2026
I've been seeing Dr Gaines for nearly 20 years. He's done my colonoscophys, treated me for hepatitis C & also cirrhosis of the liver. I recently went to see him for stomach issues. I arrived without appt by mistake & they worked me in. I highly recommend Dr Gaines & everyone in office was very nice
(2 weeks ago)
Jul-2026
Dr. Gaines is a 5 star physician. He is very knowledgeable and takes time with you to explain treatment.
(3 weeks ago)
Jul-2026
Very professional with calm demeanor.
(1 month ago)
Jul-2026
Great Dr handled everything very professional
(1 month ago)
Jul-2026
Great Dr.
(1 month ago)
Jul-2026
He was awesome. Explained the procedure well.
(1 month ago)
Jun-2026
Everything, everyone fantastic from beginning to end.
Hands down to Dr. Gaines y staff !!!!
(1 month ago)
Jun-2026
He spoke very poorly to me and my wife. To the point that he made her cry
(1 month ago)
Jun-2026
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Greenville Downtown
317 St. Francis Drive Suite 170 Greenville, SC 29601
Dr. Gaines received his undergraduate degree in biology from Birmingham-Southern College in Alabama. He continued with his education and graduated from the University of Alabama-School of Medicine, where he also completed his internship and residency. He was chosen to be the chief resident and instructor before deciding to pursue a fellowship at the Medical University of South Carolina for gastroenterology and hepatology. He chose his fellowship because he felt he connected with patients with liver disease while he was a medical student. He enjoyed the relationships he developed with people with life-threatening illnesses and the complexity of liver disease.
Dr. Gaines is presently a member of the Greenville County Medical Society, South Carolina Medical Association, South Carolina Gastroenterology Association, and American College of Gastroenterology. He is board certified with the American Board of Internal Medicine for Gastroenterology.
Dr. Gaines is originally from Alabama but enjoys the Greenville area for the outdoor opportunities. “I can be hiking in the mountains, riding my bike, or kayaking on a lake, all within an hour’s drive.”
Great
He made me feel at ease . Very personable.
I've been seeing Dr Gaines for nearly 20 years. He's done my colonoscophys, treated me for hepatitis C & also cirrhosis of the liver. I recently went to see him for stomach issues. I arrived without appt by mistake & they worked me in. I highly recommend Dr Gaines & everyone in office was very nice
Dr. Gaines is a 5 star physician. He is very knowledgeable and takes time with you to explain treatment.
Very professional with calm demeanor.
Great Dr handled everything very professional
Great Dr.
He was awesome. Explained the procedure well.
Everything, everyone fantastic from beginning to end. Hands down to Dr. Gaines y staff !!!!
He spoke very poorly to me and my wife. To the point that he made her cry