Dr. D. Isaac Gaines, M.D. received his undergraduate degree in biology from Birmingham-Southern College in Alabama. He continued with his education and graduated from the University of Alabama-School of Medicine, where he also completed his internship and residency. He was chosen to be the chief resident and instructor before deciding to pursue a fellowship at the Medical University of South Carolina for gastroenterology and hepatology.
Dr. D. Isaac Gaines, M.D. received his undergraduate degree in biology from Birmingham-Southern College in Alabama. He continued with his education and graduated from the University of Alabama-School of Medicine, where he also completed his internship and residency. He was chosen to be the chief resident and instructor before deciding to pursue a fellowship at the Medical University of South Carolina for gastroenterology and hepatology.
The reviews listed below were collected independently of Gastroenterology Associates through rater8. Each review represents an authentic and verified patient experience.
Good experience. Dr. Gaines was very nice and professional.
(2 days ago)
Oct-2026
Listens well, great doc!
(6 days ago)
Oct-2026
He is an excellent and caring doctor who spends time talking with you to determine how to best help you. Highly recommended!
(6 days ago)
Oct-2026
He answered all my questions before my operation, and the surgery went well, and my recovery without complications.
(1 week ago)
Sep-2026
I have never been to anyone that has shown me more sincere care and conversation that assured me he was genuinely interested and would do whatever he could to help me.
(1 week ago)
Sep-2026
Great! Made me feel very at ease.
(3 weeks ago)
Sep-2026
He is the best.
(3 weeks ago)
Sep-2026
Dr Gains is a great doctor. He’s always very thorough and considerate.
(1 month ago)
Sep-2026
Wonderful communicator, a pleasure to be around. A clear messenger. Thanks
(1 month ago)
Sep-2026
Very caring and easy to talk to. I'm glad I had him as my Dr
(1 month ago)
Aug-2026
Greenville Downtown
317 St. Francis Drive Suite 170 Greenville, SC 29601
Dr. Gaines received his undergraduate degree in biology from Birmingham-Southern College in Alabama. He continued with his education and graduated from the University of Alabama-School of Medicine, where he also completed his internship and residency. He was chosen to be the chief resident and instructor before deciding to pursue a fellowship at the Medical University of South Carolina for gastroenterology and hepatology. He chose his fellowship because he felt he connected with patients with liver disease while he was a medical student. He enjoyed the relationships he developed with people with life-threatening illnesses and the complexity of liver disease.
Dr. Gaines is presently a member of the Greenville County Medical Society, South Carolina Medical Association, South Carolina Gastroenterology Association, and American College of Gastroenterology. He is board certified with the American Board of Internal Medicine for Gastroenterology.
Dr. Gaines is originally from Alabama but enjoys the Greenville area for the outdoor opportunities. “I can be hiking in the mountains, riding my bike, or kayaking on a lake, all within an hour’s drive.”
Good experience. Dr. Gaines was very nice and professional.
Listens well, great doc!
He is an excellent and caring doctor who spends time talking with you to determine how to best help you. Highly recommended!
He answered all my questions before my operation, and the surgery went well, and my recovery without complications.
I have never been to anyone that has shown me more sincere care and conversation that assured me he was genuinely interested and would do whatever he could to help me.
Great! Made me feel very at ease.
He is the best.
Dr Gains is a great doctor. He’s always very thorough and considerate.
Wonderful communicator, a pleasure to be around. A clear messenger. Thanks
Very caring and easy to talk to. I'm glad I had him as my Dr